产品货号：
Z21562
中文名称：
NOGO/RTN4抗体
英文名称：
Anti-NOGO/RTN4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NOGO/RTN4 Antibody |
| 指标别名 | ASY;Foocen;KIAA0886;Nbla00271;Nbla10545;Neurite outgrowth inhibitor;NI220/250;NOGO;NOGO A;Nogo B;Nogo C;Nogo protein;NOGOA;NOGOC;NSP;NSP CL;reticulon 4;Reticulon 5;RTN X;RTN4;RTN4 A;RTN4 B1;RTN4 B2;RTN4 C;SP1507 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,ICC,IF |
| 基因名称 | RTN4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NogoA antibody was raised against a 19 amino acid synthetic peptide from near the center of human NogoA.The immunogen is located within amino acids 200 - 250 of NogoA. |
| 计算分子量 | 130kDa |
| 成分 | NogoA Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NogoA Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases.Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE.NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor.It is highly expressed in oligodendrocytes in the white matter of the CNS;blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models.NogoA has also been suggested to play a role in neurodegenerative diseases such as Amyotrophic lateral sclerosis,in which case NogoA is found at elevated levels in postmortem muscular samples,and multiple sclerosis (MS),in which case autoantibodies to NogoA have been found in serum and cerebrospinal fluid in MS patients. |
| Uniprot ID | Q9NQC3 |
| 基因名全称 | Reticulon 4 |
| 蛋白名全称 | Reticulon 4 |
| 推荐稀释比 | NogoA antibody can be used for detection of NogoA by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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